On June 18, 2018, the National Institutes of Health will host the HEALing Communities Study Design Workshop to solicit feedback from scientific experts, state partners, federal partners, and other key stakeholders. This meeting will be videocast.
NIDA is playing a major role in the National Institutes of Health (NIH) HEAL initiative (Helping to End Addiction Long-term), launched in June 2018 to provide scientific solutions to the national opioid overdose crisis, including improved treatment strategies for pain as well as opioid use disorders (OUDs). This new initiative, funded by Congress, brings new hope for people, families, and communities affected by this devastating crisis.
NIDA will be coordinating four overarching research projects around the country:
Focused OUD Medications Development Research Project
Goal: Conduct a series of high-impact studies that will ideally lead to about 15 Investigational New Drugs (INDs), which would then produce around five New Drug Applications (NDAs) submitted to the Food & Drug Administration (FDA).
This project will focus on developing new addiction treatments and overdose-reversal tools. Three medications are currently FDA-approved to treat opioid addiction, & naloxone is available in both injectable & intranasal formulations to reverse overdose. But a wider range of options is needed in both areas. These may involve new formulations of existing drugs including longer-acting depot formulations of opioid agonists as well as stronger naloxone formulations that can reverse fentanyl overdoses. Research will also focus on compounds that target different receptor systems or immunotherapies to treat symptoms of withdrawal & craving in addition to the progression of opioid use disorders.