Thursday, May 24, 2018
A new study published in the May 2018 issue of Preventive Medicine shows that African Americans & Latinos are significantly more likely to experience serious depression than Whites, but chronic stress does not seem to explain these differences. Dr. Eliseo J. Pérez-Stable, director of the National Institute on Minority Health & Health Disparities (NIMHD) was the Senior author of the study, which also found that African Americans & Latinos were more likely to have higher levels of chronic stress and more unhealthy behaviors. NIMHD is part of the National Institutes of Health.
To examine the relationship between unhealthy behaviors, chronic stress, & risk of depression by race & ethnicity, researchers used data collected on 12,272 participants, aged 40 to 70 years, from 2005 to 2012. These data were part of the National Health and Nutrition Examination Survey (NHANES), a nationally representative health interview & examination survey of U.S. adults. This age range population was selected for this study to capture the effects of chronic stress over the lifetime of the participants.
“Understanding the social & behavioral complexities associated with depression & unhealthy behaviors by race/ethnicity can help us understand how to best improve overall health,” said Pérez-Stable.
The unhealthy behaviors examined were current cigarette smoking, excessive or binge drinking, insufficient exercise, & fair or poor diet. The researchers measured chronic stress using 10 objective biological measures, including blood pressure, body mass index, & total cholesterol. The researchers assessed risk for depression using results from the Patient Health Questionnaire (PHQ-9).
Chronic stress during adulthood may be an important factor in depression. This effect may be worse among racial and ethnic minorities due to the stress experienced from social & economic inequalities, but the relationships between race/ethnicity, stress, behavior, & depression are not well understood. A theoretical framework called the Environmental Affordances model has been proposed to explain how chronic stress & risk behaviors interact to affect health. This model proposes, for example, that engaging in unhealthy behaviors actually reduces the effects of chronic stress on depression in African Americans.
The investigators designed this research to gain a better understanding of the relationship between chronic stress & chance for depression by race and ethnicity. The study asked whether unhealthy behaviors (current smoking, excessive or binge drinking, insufficient exercise, & fair or poor diet) reduce the chance for depression due to chronic stress in African Americans but increase the chance for depression due to chronic stress in Latinos, compared with Whites.
On average, Latinos & African Americans had more chronic stress, more unhealthy behaviors, & more chance for depression. However, the study found that engaging in more unhealthy behaviors was strongly associated with greater chance for depression only in African Americans & Whites.
The study also found that for all three groups:
- the level of chronic stress did not affect the relationship between unhealthy behavior and chance for depression
- unhealthy behaviors did not alter the association between stress & chance for depression
- more education offered more protection against depression
Contrary to previous research, this study found that in all three racial/ethnic groups, chronic stress levels were inversely related to excessive or binge drinking (I am.e., more stress, less excess drinking). This study also found no evidence—as some previous research has suggested—that African Americans engage in unhealthy behaviors as a way to cope with chronic stress & reduce depression or that unhealthy behaviors interact with chronic stress in Latinos to increase depression. According to the researchers the Environmental Affordances model was not supported for any of the racial/ethnic groups analyzed.
The scientists point to differences in their research design & their use of physiological measures of chronic stress instead of self-reported measures as possibly contributing to their different findings. They note that their results highlight the complex relationships between chronic stress, unhealthy behaviors, & mental health among different racial & ethnic groups.
In addition to NIMHD, the study was supported by the National Institute on Aging; the National Cancer Institute; and the National Heart, Lung, & Blood Institute, all part of NIH, & by the NIH-funded Clinical & Translational Science Institute at the University of California, San Francisco.
Grant numbers: P30AG15272, UL1RR024131-0X, U01CA86117, U54CA153511
This press release describes a basic research finding. Basic research increases our understanding of human behavior and biology, which is foundational to advancing new & better ways to prevent, diagnose, and treat disease. Science is an unpredictable & incremental process — each research advance builds on past discoveries, often in unexpected ways. Most clinical advances would not be possible without the knowledge of fundamental basic research.
About the National Institute of Minority Health and Health Disparities (NIMHD): NIMHD is one of NIH’s 27 Institutes & Centers. It leads scientific research to improve minority health & eliminate health disparities by conducting & supporting research; planning, reviewing, coordinating, & evaluating all minority health & health disparities research at NIH; promoting & supporting the training of a diverse research workforce; translating & disseminating research information; & fostering collaborations & partnerships. For more information about NIMHD, visit https://www.nimhd.nih.gov.
About the National Institutes of Health (NIH): NIH, the nation’s medical research agency, includes 27 Institutes & Centers & is a component of the U.S. Dept. of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, & translational medical research, & is investigating the causes, treatments, & cures for both common & rare diseases. For more information about NIH & its programs, visit www.nih.gov.
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Rodriquez, E. J., Livaudais-Toman, J., Gregorich, S. E., Jackson, J. S., Nápoles, A. M., & Pérez-Stable, E. J. (2018). Relationships between allostatic load, unhealthy behaviors, and depressive disorder in U.S. adults, 2005–2012 NHANES. Preventive Medicine, 110, 9–15.